• Product Name:Pregnenolone
  • Molecular Formula:C21H32O2
  • Purity:99%
  • Molecular Weight:316.484

Product Details;

CasNo: 145-13-1

Molecular Formula: C21H32O2

Appearance: white to off-white powder

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1.What is the Pregnenolone ?

Pregnenolone (PREG) is an endogenous steroid resulting from the conversion of cholesterol by the mitochondrial enzyme CYP11A1, a process that is conserved in animals from amphibians to mammalians. Pregnenolone is a steroid with specific characteristics, being the first steroid to be synthesised from cholesterol at all sites of steroidogenesis, including the brain. 

2.What is the CAS number for Pregnenolone ?

The CAS number of Pregnenolone is 145-13-1.

More information of Pregnenolone 145-13-1 are:

CAS Number



1.09 g/cm3

Melting Point

188-190 °C

Boiling Point

443.3 °C at 760 mmHg

Flash Point

188.9 °C

Vapor Pressure

1.02E-09mmHg at 25°C

Refractive Index

1.5344 (estimate)









3.What is the molecular formula of Pregnenolone ?

The chemical formula of Pregnenolone is C21H32O2 which containing 21 Carbon atoms,32 Hydrogen atoms and 2 Oxygen atoms,and the molecular weight, and the molecular weight of Pregnenolone is 316.484

4.What is Pregnenolone(145-13-1)used for?

Pregnenolone is a natural steroid hormone that serves as a precursor for a wide range of steroids, including mineralocorticoids, glucocorticoids, androgens, and estrogens. Pregnenolone can modulate myelination, neuroinflammation, neurotransmission, and neuroplasticity in the brain, implying its importance in cognition, aging, and addiction. PREG is the precursor of most steroid hormones, including the progestogens, androgens, oestrogens, glucocorticoids and mineralocorticoids.


Relevant articles related to Pregnenolone:



Alterations in Pregnenolone and Testosterone Levels in Male Shift Workers

Int. J. Environ. Res. Public Health 2023, 20(4), 3195;

The present study investigated serum pregnenolone and testosterone levels in a group of shift and daytime male workers.

Pregnenolone Inhibits Doxorubicin-Induced Cardiac Oxidative Stress, Inflammation, and Apoptosis—Role of Matrix Metalloproteinase 2 and NADPH Oxidase 1

Pharmaceuticals 2023, 16(5), 665;

Pregnenolone demonstrated both anti-inflammatory and antioxidant activity in animal models. The current study aimed to investigate the cardioprotective potential of pregnenolone against DOX-induced cardiotoxicity.

5.Pregnenolone 145-13-1 Powder In Stock.

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