979-02-2

  • Product Name:16-Dehydropregnenolone acetate
  • Molecular Formula:C23H32O3
  • Purity:99%
  • Molecular Weight:356.505
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Product Details;

CasNo: 979-02-2

Molecular Formula: C23H32O3

Appearance: White to almost white crystalline powder

Hot Sale! We supply reliable quality 979-02-2 white crystalline powder.

What is the 16-Dehydropregnenolone acetate ?

16-Dehydropregnenolone acetate is White to almost white crystalline powder, while it's Molecular Formula is C23H32O3. 16-Dehydropregnenolone acetate (16-DPA), an important intermediate for preparation of steroidal drugs, is the dehydration product of Pregnenolone Acetate (). 16-Dehydropregnenolone acetate (16-DPA), which possesses α-β unsaturated carbonyl group, finds increasing application as a versatile scaffold and building block for the synthesis of different steroidal drugs like dexamethasone, β-methasone, 5α-reductase inhibitor and other related steroidal pharmacophores.

What is the CAS number for 16-Dehydropregnenolone acetate ?

The CAS number of 16-Dehydropregnenolone acetate is 979-02-2.

More information of 16-Dehydropregnenolone acetate 979-02-2 are:

Synonyms

20-oxopregna-5,16-dien-3-β-yl acetate;16-Denyprasterone Acetate;16-Denyprasterone Acetate(16-DPA);16-Dehydropregnenolone Acetate(16-DPA);16 Dehydropregneninolone, Acetate;Pregna-5,16-dien-20-one, 3- (acetyloxy)-, (3.beta.)-;20-Oxopregna-5, 16-dien-3.beta.-yl acetate;Dehydropregnenolone acetate;Pregna-5,16-dien-20-one, 3-beta-hydroxy-, acetate;Pregna-5,16-dien-20-one, 3beta-hydroxy-, acetate (8CI);4-08-00-01125 (Beilstein Handbook Reference);16,17-Didehydropregnenolone acetate;3.beta.-Acetoxypregna-5,16-dien-20-one;20-Oxopregna-5,16-dien-3-beta-yl acetate;(3-beta)-3-(Acetyloxy)pregna-5,16-dien-20-one;Pregna-5,16-dien-20-one, 3.beta.-hydroxy-, acetate;

CAS Number

979-02-2

Molecular Formula

C23H32O3

Molecular Weight

356.505

Density

1.11g/cm3

Melting Point

170-178 °C

Boiling Point

464.4 °C at 760mmHg

Flash Point

200.1 °C

PSA

43.37000

LogP

5.00620

What is 16-Dehydropregnenolone acetate (979-02-2) used for?

16-Dehydropregnenolone Acetate is used in the preparation of pregnane derivatives and its glycosides as potential anticancer agents. A stereoselective total synthesis of naturally occurring 20-epi cholanic acid derivatives has been realized, starting from readily available 16-dehydropregnenolone acetate. Novel sulphur derivatives have been synthesized for the first time from 16-Dehydropregnenolone acetate (16-DPA) by adopting thia-Michael addition reaction yielding 2-[(3β-acetoxy) pregn–5-ene-20-one −16 –thio] propanoic acid, 2-[(3β-acetoxy) pregn–5-ene-20-one–16–thio] ethanoic acid, 3β-acetoxy 16α-(2-hydroxyethylthio)-pregn-5-ene-20-one and 3β-acetoxy-16β-(2-amino phenylthio)-pregn-5-ene-20-one.

InChI:InChI=1/C23H32O3/c1-14(24)19-7-8-20-18-6-5-16-13-17(26-15(2)25)9-11-22(16,3)21(18)10-12-23(19,20)4/h5,7,17-18,20-21H,6,8-13H2,1-4H3/t17-,18-,20-,21-,22-,23+/m0/s1

Articles related to 16-Dehydropregnenolone acetate:

Article

Source

A study on the reaction of 16-dehydropregnenolone acetate with 2-aminobenzimidazole

Author links open overlay panelAgnieszka Wojtkielewicz, Paulina Uścinowicz, Leszek Siergiejczyk, Urszula Kiełczewska, Artur Ratkiewicz, Jacek W. Morzycki

Steroids Volume 117, January 2017, Pages 71-76

Synthesis of Steroidal Thioethers via [HDBU][OAc]‐Mediated Michael Addition of Thiols to 16‐Dehydropregnenolone

Lilla Maksó, Krisztina Kovács, Kitti Andreidesz, Ágnes Gömöry, Sándor Mahó, Rita Skoda-Földes

ChemistrySelect, Volume7, Issue29 August 5, 2022 e202200967

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