51022-70-9

  • Product Name:Albuterol sulfate
  • Molecular Formula:2(C13H21NO3).H2O4S
  • Purity:99%
  • Molecular Weight:576.709
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Product Details;

CasNo: 51022-70-9

Molecular Formula: 2(C13H21NO3).H2O4S

Appearance: white crystalline solid

Albuterol sulfate Good Supplier In Bulk Supply High Purity 51022-70-9

  • Molecular Formula:2C13H21NO3*H2O4S
  • Molecular Weight:576.709
  • Appearance/Colour:white crystalline solid 
  • Vapor Pressure:8.92E-08mmHg at 25°C 
  • Melting Point:180 °C 
  • Boiling Point:433.5 °C at 760 mmHg 
  • Flash Point:159.5 °C 
  • PSA:155.70000 
  • LogP:2.12490 

Albuterol sulfate(Cas 51022-70-9) Usage

Biological Activity

Non-selective β -adrenergic agonist, more potent at β 2 than β 1 receptors.

Veterinary Drugs and Treatments

Albuterol is used principally in dogs and cats for its effects on bronchial smooth muscle to alleviate bronchospasm or cough. It is also used in horses as a bronchodilator.

Mode of action

Albuterol Sulfate is the sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of (R)-albuterol and (S)-albuterol with bronchodilator activity. Albuterol stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. To a lesser extent albuterol stimulates beta1-adrenergic receptors, thereby increasing the force and rate of myocardial contraction.

Definition

ChEBI: Albuterol sulfate is an ethanolamine sulfate salt. It is functionally related to an albuterol.

Brand name

Accuneb (Dey); Proair (IVAX); Proventil (Schering); Ventolin (GlaxoSmithKline); Volmax (Muro); Vospire (Odyssey).

General Description

Albuterol belongs to the class of medicines known as bronchodilators. It is also called a short-acting beta-agonist (SABA).

InChI:InChI=1/2C12H19NO3.H2O4S/c2*1-12(2,3)13-7-11(16)8-4-5-9(14)10(15)6-8;1-5(2,3)4/h2*4-6,11,13-16H,7H2,1-3H3;(H2,1,2,3,4)

51022-70-9 Relevant articles

Process for the enantiomeric enrichment of salbutamol and salbutamol precursors

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Page/Page column 10, (2008/06/13)

The present invention relates to a proce...

Drug delivery system

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, (2008/06/13)

A drug delivery system in which a taste ...

51022-70-9 Process route

R-salbutamol*pivalic acid

R-salbutamol*pivalic acid

salbutamol sulfate
34245-12-0,36519-31-0,39971-61-4,51022-70-9,65143-06-8,148563-15-9,148563-16-0,324000-05-7,324000-04-6

salbutamol sulfate

Conditions
Conditions Yield
With sulfuric acid; In methanol; for 0.5h;
90%
salbutamol sulfate
34245-12-0,36519-31-0,39971-61-4,51022-70-9,65143-06-8,148563-15-9,148563-16-0,324000-05-7,324000-04-6

salbutamol sulfate

Conditions
Conditions Yield

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