67165-56-4
- Product Name：Diclofensine
- Molecular Formula：C17H17Cl2NO
- Purity：99%
- Molecular Weight：322.234
Product Details;
CasNo： 67165-56-4
Molecular Formula： C17H17Cl2NO
Quality products make an important contribution to long-term revenue and profitability. High purity API 67165-56-4 fast delivery.
1.What is the Diclofensine ?
Diclofensine is an antidepressant drug containing a dichloroarene-substitutedtetrahydroisoquinoline. A stimulant; inhibits reuptake of dopamine and noradrenaline, is an effective antidepressant. Compound exhibits significant addictive properties.
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- 802051-24-7
1-(3,4-dichlorophenyl)-2-((3-methoxybenzyl)(methyl)amino)ethanol
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- 692248-97-8
4-(3,4-dichlorophenyl)-5-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
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- 67165-56-4
Diclofensine
| Conditions | Yield |
|---|---|
|
1-(3,4-dichlorophenyl)-2-((3-methoxybenzyl)(methyl)amino)ethanol; With sulfuric acid; In dichloromethane; at 0 ℃; for 28h;
With sodium hydroxide; In dichloromethane; pH=9;
|
59% 10% |
|
1-(3,4-dichlorophenyl)-2-((3-methoxybenzyl)(methyl)amino)ethanol; With sulfuric acid; In dichloromethane; at 0 ℃; for 28h;
With sodium hydroxide; In dichloromethane; pH=~ 9;
|
|
|
1-(3,4-dichlorophenyl)-2-((3-methoxybenzyl)(methyl)amino)ethanol; With sulfuric acid; In dichloromethane; water; at 0 ℃; for 28h;
With sodium hydroxide; In dichloromethane; water; pH=~ 9;
|
-
- 1254941-88-2
1-(3,4-dichlorophenyl)-2-((3-methoxybenzyl)(methyl)amino)ethanone
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- 67165-56-4
Diclofensine
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 2 steps
1.1: sodium tetrahydroborate / methanol / 2 h / 0 °C
2.1: sulfuric acid / dichloromethane; water / 28 h / 0 °C
2.2: pH ~ 9
With sodium tetrahydroborate; sulfuric acid; In methanol; dichloromethane; water;
|
2.What is the CAS number for Diclofensine ?
The CAS number of Diclofensine is 67165-56-4.
More information of Diclofensine 67165-56-4 are:
|
CAS Number |
67165-56-4 |
|
Density |
1.242 g/cm3 |
|
Boiling Point |
422.595 °C at 760 mmHg |
|
Flash Point |
209.378 °C |
|
Vapor Pressure |
2.38E-07mmHg at 25°C |
|
Refractive Index |
1.59 |
| Canonical SMILES | CN1CC(C2=C(C1)C=C(C=C2)OC)C3=CC(=C(C=C3)Cl)Cl |
| XLogP3-AA | 4.5 |
| Complexity | 354 |
|
HS CODE |
2933499090 |
|
PSA |
12.47000 |
|
LogP |
4.51720 |
|
Pka |
7.87±0.40(Predicted) |
3.What are another words for Diclofensine ?
Synonyms for Diclofensine 67165-56-4:Ro 8-4650;Diclofensine;4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-7-methoxy-2-methylisoquinoline;
4.What is the molecular formula of Diclofensine?
The chemical formula of Diclofensine is C17H17Cl2NO which containing 17 Carbon atoms,17 Hydrogen atoms,2 Chlorine atoms,1 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of Diclofensine is 322.234.
5.What is Diclofensine (67165-56-4) used for?
Diclofensine is a stimulant drug showing antidepressant and monoamine reuptake inhibitor activity.
InChI:InChI=1/C17H17Cl2NO/c1-20-9-12-7-13(21-2)4-5-14(12)15(10-20)11-3-6-16(18)17(19)8-11/h3-8,15H,9-10H2,1-2H3
Relevant articles related to Diclofensine:
|
Article |
Source |
| Exploring Electrochemical C(sp3)–H Oxidation for the Late-Stage Methylation of Complex Molecules |
A diclofensine analogue underwent Shono oxidation and methylation, without purification of the intermediate, to give product 27 in high yield with an excellent diastereomeric ratio. , J. Am. Chem. Soc. 2022, 144, 3, 1187–1197 |
| Gold(I)‐Catalyzed Alkynylation of N,O‐Acetals: An Access to Alkynylated Saturated N‐heterocycles |
To explore this challenging approach, we selected the protected tetrahydroisoquinoline 4, which is structurally related to diclofensine, a known stimulant drug.This example was … , Advanced Synthesis & Catalysis, 2023 |
6.High purity API 67165-56-4 fast delivery.
Shandong Hanjiang Chemical Co., Ltd. is a quality supplier of Diclofensine, fast delivery. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on high purity API Diclofensine 67165-56-4.
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