
183814-30-4
- Product Name:Formoterol Fumarate
- Molecular Formula:2(C19H24N2O4).C4H4O4.2(H2O)
- Purity:99%
- Molecular Weight:840.925
Product Details;
CasNo: 183814-30-4
Molecular Formula: 2(C19H24N2O4).C4H4O4.2(H2O)
Appearance: Pale yellow solid
Manufacturer supply top purity Formoterol Fumarate 183814-30-4 with GMP standards
- Molecular Formula:C4H4O4*2C19H24N2O4*2H2O
- Molecular Weight:840.925
- Appearance/Colour:Pale yellow solid
- Vapor Pressure:2.12E-15mmHg at 25°C
- Melting Point:116-120 °C
- Boiling Point:603.2oC at 760 mmHg
- Flash Point:318.6oC
- PSA:274.70000
- LogP:6.22940
(R*,R*)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide fumarate dihydrate(Cas 183814-30-4) Usage
Biological Activity |
Potent, selective and long-acting β 2 -adrenoceptor agonist. Displays 330-fold selectivity for β 2 over β 1 receptors (pK d values are 8.12 and 5.58 respectively). Potently relaxes guinea pig trachea (pD 2 = 9.29), and is longer-acting and 100-fold more potent than salbutamol. |
Biochem/physiol Actions |
β2-Adrenoreceptor agonist. |
InChI:InChI=1/C19H24N2O4.C4H4O4.2H2O/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22;5-3(6)1-2-4(7)8;;/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22);1-2H,(H,5,6)(H,7,8);2*1H2/b;2-1+;;/t13-,19+;;;/m1.../s1
183814-30-4 Relevant articles
Preparation method and application of formoterol and medicinal salt thereof
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Paragraph 0098-0100, (2021/03/31)
The invention provides a preparation met...
AN IMPROVED PROCESS FOR THE PREPARATION OF HIGH PURITY FORMOTEROL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS
-
Page/Page column 21; 25, (2010/11/30)
The present invention relates to an impr...
Novel aerosol formulation containing a polar fluorinated molecule
-
, (2008/06/13)
The present invention relates to a stabl...
183814-30-4 Process route
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128954-45-0,67346-49-0
formoterol

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110-17-8,26099-09-2
(2E)-but-2-enedioic acid

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-
183814-30-4
formoterol fumarate dihydrate
Conditions | Yield |
---|---|
With
water;
In
ethanol;
at 25 ℃;
|
95.6% |
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-
87833-61-2
formoterol hemifumarate

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-
183814-30-4
rac-(N-[2-hydroxy-5-[(1RS)-1-hydroxy-2-[[(1RS)-2-(4-methoxyphenyl)-1-methylethyl]-amino]ethyl]phenyl]formamide) fumarate dihydrate
Conditions | Yield |
---|---|
With
water;
at 25 - 30 ℃;
for 0.5h;
Product distribution / selectivity;
|
183814-30-4 Upstream products
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formoterol hemifumarate
-
formoterol
-
(2E)-but-2-enedioic acid
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