183814-30-4

  • Product Name:Formoterol Fumarate
  • Molecular Formula:2(C19H24N2O4).C4H4O4.2(H2O)
  • Purity:99%
  • Molecular Weight:840.925
Inquiry

Product Details;

CasNo: 183814-30-4

Molecular Formula: 2(C19H24N2O4).C4H4O4.2(H2O)

Appearance: Pale yellow solid

Manufacturer supply top purity Formoterol Fumarate 183814-30-4 with GMP standards

  • Molecular Formula:C4H4O4*2C19H24N2O4*2H2O
  • Molecular Weight:840.925
  • Appearance/Colour:Pale yellow solid 
  • Vapor Pressure:2.12E-15mmHg at 25°C 
  • Melting Point:116-120 °C 
  • Boiling Point:603.2oC at 760 mmHg 
  • Flash Point:318.6oC 
  • PSA:274.70000 
  • LogP:6.22940 

(R*,R*)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide fumarate dihydrate(Cas 183814-30-4) Usage

Biological Activity

Potent, selective and long-acting β 2 -adrenoceptor agonist. Displays 330-fold selectivity for β 2 over β 1 receptors (pK d values are 8.12 and 5.58 respectively). Potently relaxes guinea pig trachea (pD 2 = 9.29), and is longer-acting and 100-fold more potent than salbutamol.

Biochem/physiol Actions

β2-Adrenoreceptor agonist.

InChI:InChI=1/C19H24N2O4.C4H4O4.2H2O/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22;5-3(6)1-2-4(7)8;;/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22);1-2H,(H,5,6)(H,7,8);2*1H2/b;2-1+;;/t13-,19+;;;/m1.../s1

183814-30-4 Relevant articles

Preparation method and application of formoterol and medicinal salt thereof

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Paragraph 0098-0100, (2021/03/31)

The invention provides a preparation met...

AN IMPROVED PROCESS FOR THE PREPARATION OF HIGH PURITY FORMOTEROL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS

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Page/Page column 21; 25, (2010/11/30)

The present invention relates to an impr...

Novel aerosol formulation containing a polar fluorinated molecule

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, (2008/06/13)

The present invention relates to a stabl...

183814-30-4 Process route

formoterol
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(2E)-but-2-enedioic acid
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(2E)-but-2-enedioic acid

formoterol fumarate dihydrate
183814-30-4

formoterol fumarate dihydrate

Conditions
Conditions Yield
With water; In ethanol; at 25 ℃;
95.6%
formoterol hemifumarate
87833-61-2

formoterol hemifumarate

rac-(N-[2-hydroxy-5-[(1RS)-1-hydroxy-2-[[(1RS)-2-(4-methoxyphenyl)-1-methylethyl]-amino]ethyl]phenyl]formamide) fumarate dihydrate
183814-30-4

rac-(N-[2-hydroxy-5-[(1RS)-1-hydroxy-2-[[(1RS)-2-(4-methoxyphenyl)-1-methylethyl]-amino]ethyl]phenyl]formamide) fumarate dihydrate

Conditions
Conditions Yield
With water; at 25 - 30 ℃; for 0.5h; Product distribution / selectivity;

183814-30-4 Upstream products

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    87833-61-2

    formoterol hemifumarate

  • 128954-45-0
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    formoterol

  • 110-17-8
    110-17-8

    (2E)-but-2-enedioic acid